arteries of today's obese or diabetic young people bodes ill for their
future health, researchers report.
The walls of these carotid arteries, which carry blood to the brain,
showed a thickening and stiffness known to increase the risk of future
strokes, heart attacks and other cardiovascular problems, according to a
report to be published in the June 9 issue of Circulation.
"Since the 1980s, there has been a major increase in obesity in our
youth," said Dr. Elaine Urbina, director of preventive cardiology at
Cincinnati Children's Hospital Medical Center, associate professor of
pediatrics at the University of Cincinnati and lead author of the report.
"This could be the first generation of Americans that has a shorter life
expectancy than its parents," she said.
In the study, Urbina and her team used ultrasound to assess the carotid
arteries of a few hundred young people (average age 18) � 182 who were
lean, 128 diagnosed with type 2 diabetes (often tied to obesity), and 136
classified as obese because their weight-for-height was above the 95th
percentile. "It was one of the larger studies of carotid thickness in
adolescents," Urbina said.
The researchers looked at the thickness of the intima, one of the
layers of tissue that line the arteries.
"If you have diabetes, the intima is thicker than if you don't have
diabetes," Urbina said. "If you are obese, the artery is also thicker.
Stiff carotids are linked to heart attacks as well as strokes, because if
you are having a buildup of plaque in the arteries that lead to the brain,
you probably are having a buildup in the coronary arteries as well."
Plaque is the term for the fatty deposits that can increase in size and
thickness until they limit or totally block normal blood flow.
The young people who were obese or had diabetes were more likely to
have other risk factors for cardiovascular disease, such as higher blood
pressure and high levels of blood fats such as cholesterol, the study
found. But those factors did not account for the significant changes in
artery structure and function, the researchers said.
According to Urbina, the detection of unhealthy artery changes in
young, obese or diabetic people "demonstrates the need for research in
this area."
One expert said the findings reinforce prior research.
"This is more evidence that obesity is not good for young people," said
Dr. Robert H. Eckel, professor of physiology and biophysics at the
University of Colorado, a spokesman for the American Heart Association.
However, it's not clear from the study how damaging obesity might be in
these young people, Eckel said.
"How important [the findings are] in terms of what is to follow is not
clear," he said, noting that the consequences for adult health of obesity
in childhood are not set in stone.
"There can be intervention to modify risk, not necessarily to reduce
obesity but to control blood pressure and blood lipids more aggressively.
I would like to see further studies that follow these young people with
and without intervention for 10 years," Eckel said.
In the meantime, rising childhood obesity is now a troubling fact of
life for doctors who see young patients, Urbina added. A kilogram equals
2.2 pounds, and "at least once a month, I see a child who weighs more in
kilograms than I weigh in pounds," she said. "Yesterday, I saw that in an
11-year-old."
The child and youth obesity problem is an issue for schools as well as
parents, Urbina said. Schools must play a role, because "80 percent of the
calories children consume are outside the control of parents," she said,
and also because schools often do not emphasize physical activities that
can help prevent excess weight gain.
"We need better nutrition and better after-school programs," she
said.
More information
There's more on obesity in the United States at the U.S. Centers
for Disease Control and Prevention.
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